Adhesive cream for dental prostheses

ABSTRACT

Improved composition of a fixing cream containing at least one oil and/or fat, preferably plant oil, such as, for example, an olive oil, at least one water-soluble polymer selected from the group of cellulose derivatives, at least one alkyl vinyl ether/maleic acid anhydride copolymer and, as the additional substances, at least trihydroxystearin.

FIELD OF THE INVENTION

The invention relates to fixing cream compositions according to thepreambles of claims 1 and 3.

PRIOR ART

Many commercial fixing cream compositions for prosthetic teeth are basedon a mixture of refined paraffins, water-soluble cellulose derivativepolymers and alkyl vinyl ether/maleic acid anhydride copolymers.Conventionally, mineral oils and mineral fats, in particular Vaseline,are used. Mineral oils and fats generally constitute approximately 40%by weight or more of the fixing cream composition.

Since a fixing cream slowly dissolves in the mouth during use, on theone hand there is the possibility that components of the cream enter thebody via the mucous membranes of the mouth and pharynx and, on the otherhand, components reach the digestive tract with the saliva and the foodand may subsequently become distributed throughout the body. The basiccomponents of Vaseline and mineral oil are not completely harmlessaccording to the most recent results of research. Vaseline, for example,appears to promote blastomycosis conditions in newborn babies.Consequently, negative effects in adults cannot be excluded. Cautionappears to be demanded particularly in the regular use of mineral oilson mucous membranes. Therefore, a replacement for mineral oils andmineral fats would be desirable.

In order to improve adhesion, zinc-containing substances are generallyadded. Such commercial fixing cream products have a zinc content of from1.7 to 3.4% by weight according to in-house analyses. In document U.S.Pat. No. 4,758,630, a zinc content of from 1 to 2.4% by weight of thetotal amount of fixing cream composition is recommended. Recently, ithas also become known that greater absorption of zinc compounds by theorganism which had previously been thought to be harmless sometimescauses irreversible symptoms of poisoning. With regular use, therefore,the zinc compounds in the fixing cream could have similar effects. Inorder to prevent toxic symptoms in tooth prosthesis wearers, there is aneed for a fixing cream formulation which also has excellent wearingproperties and storability with addition of zinc compounds which isreduced or dispensed with.

Furthermore, commercial base products which are used in the productionof fixing creams in any case contain traces of zinc impurities such as,for example, Gantrez® MS955, a methyl vinyl ether/maleic acid anhydridecopolymer which is often used in the production of fixing creams.Analyses have shown that this base product contains 4.8 mg of zinc perkilogram. As a result, a content of approximately 2 ppm of zinc, but amaximum of 4.8 ppm of zinc, may be anticipated in a fixing creamproduced therewith. However, the proportion of zinc compounds which maybe contained in such base products is far lower than that which ismeasured—as mentioned above—in commercial fixing creams and originatesfrom selective addition.

If currently existing formulations with a methyl vinyl ether/maleic acidanhydride copolymer could be modified in such a manner that it ispossible to dispense, partially or completely, with mineral oils and/orVaseline and additionally included zinc compounds, there would result aproduct which can be regarded as being harmless to health. In particularthe use of plant oils and fats would correspond to the current healthconsciousness of consumers.

The contents and the quantitative relationships determine the propertiesof a fixing cream. The properties include, for example, the adhesionstrength, the adhesion duration, the wearing comfort, the taste, theconsistency, the stability, etcetera. In order to adjust the adhesionparameters such as adhesion duration and adhesion strength, a givenproportion of Zn²⁺ compounds is added in commercial products on amineral oil basis. The adhesion strength and the adhesion duration arepositively influenced by the addition of zinc compounds according todocument U.S. Pat. No. 4,758,630 and, consequently, the addition of zinccompounds is of great significance to the usability of the fixing cream.

As mentioned above, paraffins such as refined mineral oils and fats(Vaseline) are used in many commercial fixing creams. These areadmixtures of saturated hydrocarbons having the general molecularformula C_(n)H_(2n+2), this involving liquid products (oils) or greasyto solid products (fats) in accordance with the distillation degree. Themineral oil admixtures and fats which are used in cosmetics and medicinealso consist of practically exclusively saturated hydrocarbons. Thepurity of the admixtures depends on the degree of refinement. The degreeof refinement is high for cosmetic and medical use. It is therebyintended to be ensured that carcinogenically acting polycyclicalaromatic hydrocarbons are removed from the admixture as completely aspossible.

Mineral oils and fats are often used as bases of skin creams, the effectthereof being graded differently in this instance. Acknowledged groupsof experts are of the opinion that paraffins can prevent the naturalregulation mechanisms of the human body. In particular, they canaccumulate in the liver, kidney and lymph nodes. However, there isuncertainty as to whether the paraffins can penetrate the skin. It isgenerally assumed that paraffins do not penetrate the skin in the caseof topical application and therefore there is also no risk from thosesubstances. Cosmetic skin creams having oils and fats have been on themarket for many years. In the case of use in fixing creams, however,there is an increased probability that paraffinic components will beabsorbed directly by the body via the digestion.

U.S. Pat. No. 5,561,177 discloses a fixing cream formulation which isproduced on the basis of plant oils. Accordingly, oils whichparticularly contain triglycerides of saturated fatty acids can besuccessfully used. Those triglycerides further have carbon chains ofmedium length, that is to say, chains having 8 or 10 carbon atoms in thefatty acid radical, which do not correspond to the typical fatty acidrange of plant oils and fats (C₁₂-C₂₀). The use of oils which containunsaturated fatty acids is not recommended. According to U.S. Pat. No.5,561,177, oils which contain unsaturated fatty acid esters have thedisadvantage that they become unstable at high temperatures or afterbeing stored for a given time. Furthermore, fixing creams which containsuch oils are less solid owing to the unsaturated double-bonds present,that is to say, too liquid to be used as a fixing cream.

OBJECT OF THE INVENTION

An object of the present invention is to formulate a fixing creamcomposition which has good adhesive strength and is stable in the longterm. Furthermore, the fixing cream composition is intended to be basedon predominantly natural and physiologically harmless base products. Inparticular, there is intended to be found a formulation which is alsofree from mineral oils and free from zinc-containing compounds or whichmay have good fixing cream properties with a low content of mineral oiland/or zinc. Another object is to produce a fixing cream which isimproved in physiological terms and which is at least equivalent interms of its stability properties and adhesion properties, in particularwith regard to the adhesion duration and the adhesion strength, incomparison with commercial creams. Furthermore, a fixing cream whichproduces a pleasant sensation in the mouth is sought.

DESCRIPTION

According to the invention, the object is achieved in a firstconstruction with a fixing cream composition according to claim 1 inthat the composition of a fixing cream which contains

a) at least one oil or fat, preferably of a plant type, b) at least onewater-soluble polymer selected from the group of cellulose derivativesand c) at least one alkyl vinyl ether/maleic acid anhydride copolymer,is characterised in that d) at least trihydroxystearin is containedtherein.

It has surprisingly been found that the adhesion properties of thefixing cream are improved by the addition of trihydroxystearin.

Other substances selected from the group consisting of silicon dioxide,phosphoglycerides and polyethylene glycols can advantageously be addedin order to further improve the properties.

According to the invention, the object is achieved in a secondconstruction in that the composition of a fixing cream which

contains a) at least one plant oil or fat, b) at least one water-solublepolymer selected from the group of cellulose derivatives and c) at leastone alkyl vinyl ether/maleic acid anhydride copolymer, is characterisedin that the fatty acid content (the term fatty acid content beingintended to refer below to the fatty acid bound as an ester) of theplant oil and/or fat contained consists of at least 20% by weight ofunsaturated fatty acids.

The composition according to the invention has the advantage that itcomprises physiologically completely harmless components and istherefore also harmless when used for a relatively long time.Surprisingly, it was possible to find a composition which ensures verygood and long-lasting adhesion in spite of a high proportion ofunsaturated fatty acids. Good storage stability was also able to beachieved.

It has surprisingly been found that the flowability and the consistencyof the cream can be positively influenced by the addition of silicondioxide. A tendency towards liquefaction can effectively be prevented bysilicon dioxide.

In this construction of the invention which is characterised in that theplant oil or fat contains a given minimum unsaturated fatty acidproportion, particularly advantageous adhesion properties are obtainedif the composition of the fixing cream contains additional substancesselected from the group consisting of phosphoglycerides,trihydroxystearin and polyethylene glycols.

According to the invention, the object is achieved in a thirdconstruction with a fixing cream composition according to claim 3 inthat the composition of a fixing cream which contains a) at least oneoil or fat, preferably of the plant type, b) at least one water-solublepolymer selected from the group of cellulose derivatives and c) at leastone alkyl vinyl ether/maleic acid anhydride copolymer, is characterisedin that d) at least one polyethylene glycol is contained therein.

In the case of this third construction, it is advantageous for thecomposition of the fixing cream to contain at least one other substanceselected from the group consisting of silicon dioxide, phosphoglyceridesand trihydroxystearin.

The following description relates to all the constructions set outabove.

It has surprisingly been established that the high proportion of zinccompounds normally added in order to adjust the adhesion parameters canbe dispensed with if one or a plurality of plant oils and/or fats areused simultaneously. Plant oils and fats are obtained from the seeds orfruits of oily plants. In chemical terms, plant oils and fats are estersof glycerin with fatty acids, often with three fatty acids, so-calledtriglycerides. Many plant oils are regularly taken up by humans withfoodstuffs and are physiologically completely harmless in the quantitieswhich generally occur in the food. Examples of the oils and fats whichcan be used in the fixing cream composition according to the inventionare olive oil, rapeseed oil, peanut oil, maize oil, wheat-germ oil,walnut oil, grapeseed oil, sunflower oil, wheat-germ oil, sesame oil,palm oil, palm seed oil, poppy oil, linseed oil, pumpkin seed oil,thistle oil, evening primrose oil, hemp oil and coconut fat. In thisinstance, olive oil is preferably used because it results in aparticularly physiologically tolerable fixing cream which is accepted interms of taste, with the addition of zinc compounds simultaneously beingdispensed with. As known, refined olive oil has a relatively neutraltaste, is readily available and is generally known to be healthy anddigestible. A particular advantage of olive oil is also that it has anantiseptic and antibacterial effect. Tests have shown that,surprisingly, olive oil substantially inhibits the growth of organisms(bacteria, fungi) between the gums and the prosthesis. In particular, itwas also possible to establish that the fungus Candida albicans can beinhibited by means of the fixing cream enriched with olive oil.

Particularly surprising results are achieved with the combination ofplant oils in fixing creams with silicon dioxide additives. Plant oilsand fats are liquid, or at least highly flowable, owing to their highdouble-bond proportions. In order to prevent the fixing cream fromflowing away under the prosthesis and, at the same time, to influencethe adhesion properties, various stabilisers can be introduced into thefixing cream admixture. Silicon dioxide has been found to beparticularly suitable. In particular, not only is a long adhesionduration achieved with constantly good adhesion strength, but also thestability is provided under adverse environmental conditions, such as,for example, during transport of the cream in aircraft at reducedpressure or during storage in elevated mountain locations. Silicondioxide (SiO₂) is available in various forms and qualities. Silicondioxide in the form of highly dispersed silicon dioxide is preferablyused (that is to say, in the form of an amorphous silicic powderproduced by means of flame methods), also known as pyrogenic silicicacid (Aerosil®).

Consequently, the fixing cream according to the invention isdistinguished by a composition which is harmless to health and which isbased on plant oils and/or fats, in particular olive oil. In thisinstance, olive oil may equally be used in the partially refined and theunrefined state. Cold-pressed olive oil and olive oil produced in aprotective manner without any excessive temperature effect from a firstpressing is advantageously used (that is to say, native extra virginolive oil).

In addition to silicon dioxide, trihydroxystearin and polyethyleneglycol also result in stable fixing cream compositions. These substancesprovide good results both for creams on the basis of plant oils and forcreams on the basis of mineral oils.

The fixing cream advantageously contains in relation to the totalquantity of the composition:

a) from 25 to 60% by weight of at least one oil and/or fat, preferablyplant oil and/or fat,

b) from 10 to 40% by weight of at least one water-soluble polymerselected from the group of cellulose derivatives,

c) from 25 to 45% by weight of at least one alkyl vinyl ether/maleicacid anhydride copolymer,

d) from 0 to 15% by weight of polyethylene glycols or optionally up to15% by weight of polyethylene glycols,

e) from 0 to 3% by weight of phosphoglycerides or optionally up to 3% byweight of phosphoglycerides,

f) from 0 to 2.5% by weight of trihydroxystearin or optionally up to2.5% by weight of trihydroxystearin,

g) from 0 to 5% by weight of silicon dioxide or optionally up to 5% byweight of silicon dioxide, and

h) from 0 to 10% by weight of other additives.

Most additional additives are expediently selected from the group ofantioxidants, flavourings, colourings, stabilisers, thickeners,emulsifiers and admixtures thereof. In this instance, a substance maybelong to a plurality of effective groups, or have a plurality ofeffects.

The stabilisers act in an emulsifying, thickening manner and prevent thecomponents from becoming separated. According to the invention, they areselected from the group containing silicon dioxide, trihydroxystearin,phosphoglycerides and polyethylene glycols. These substances havecomplex effect mechanisms and can influence each other—in accordancewith our experiences—synergistically. The stability of a fixing cream issignificant during storage and keeping and for the duration of use.During storage and keeping, moisture, temperature and pressure aregenerally relatively constant. In the course of use, however, oralsaliva, food and changing pressure and temperature conditions furtheract on the fixing cream. Owing to this changing requirement, it may beadvantageous to add different stabiliser substances which in total inthe case of the different environmental influences improve andparticularly stabilise the fixing cream properties. Thickeners are usedas stabilisers. Thickeners which are also referred to as thickeningstabilisers are preferably added in a quantity of from 0.001 to 3% byweight in relation to the total quantity of the composition. The use ofsilicon dioxide is expedient in a quantity of from 0.001 to 5% byweight, preferably from 0.1 to 4% by weight and more preferably from 0.5to 3% by weight in relation to the total quantity of the composition.Particular advantages are involved in the use of silicon dioxide incombination in a cream on the basis of plant oil and/or fat. It isadvantageous to use trihydroxystearin and/or phosphoglycerides such as,for example, lecithins. Trihydroxystearin is advantageously used in aquantity of from 0.001 to 2.5% by weight in relation to the totalquantity of the composition and has an emulsifying and thickeningeffect. There is preferably used a quantity with a lower limit of 0.001%by weight and more preferably 0.01% by weight of trihydroxystearin andan upper limit of 2.0% by weight, more preferably of 1.5% by weight andeven more preferably of 0.5% by weight of trihydroxystearin, the upperlimits and lower limits being able to be freely combined. Polyethyleneglycols are advantageously added in a quantity of from 0.001 to 15% byweight, preferably from 3 to 12% by weight and more preferably from 5 to9% by weight in relation to the total quantity of the composition. Thereare particularly preferably used polyethylene glycols having a molarmass of from 100,000 to 7,000,000 g/mol, in particular from 200,000 to400,000 g/mol. Phosphoglycerides are advantageously used in a quantityof from 0.001 to 3% by weight in relation to the total quantity of thecomposition and act in an emulsifying and softening manner. There ispreferably used a quantity with a lower limit of 0.001% by weight andmore preferably 0.01% by weight of phosphoglyceride and an upper limitof 2% by weight, more preferably of 1% by weight, more preferably of0.5% by weight of phosphoglyceride, the upper limits and lower limitsbeing able to be freely combined. If phosphoglycerides such as, forexample, lecithin and trihydroxystearin, are present together asstabilisers, the total quantity of stabiliser additive can surprisinglybe reduced. If phosphoglycerides and trihydroxystearin are present incombination, phosphoglycerides are advantageously used in a quantity offrom 0.001 to 3% by weight, more preferably in a quantity of from 0.001to 2% by weight, particularly preferably in a quantity of from 0.01 to1% by weight, and trihydroxystearin in a quantity of from 0.001 to 2.5%by weight, particularly preferably in a quantity of from 0.001 to 1% byweight, and very particularly preferably in a quantity of from 0.01 to0.5% by weight in relation to the total quantity of the composition.Phosphoglycerides, in particular lecithin, more particularly soyalecithin, appear to act in a predominantly stabilising manner on thefixing cream composition. Stearins, in particular trihydroxystearin,further increase the adhesion strength of the cream.

In addition to the used stabilisers from the group containing silicondioxide, trihydroxystearin and phosphoglycerides, other stabilisers orfilling substances which act in a thickening manner can be used such as,for example, polyethylene glycol or talcum. Silicon dioxide ortrihydroxystearin are preferred as stabilisers which act in a thickeningmanner.

An expedient aspect is the combination of the two additivesphosphoglycerides and trihydroxystearin, in particular lecithin andtrihydroxystearin, with at least one other additive or both additivesfrom the group comprising silicon dioxide and polyethylene glycol.

It is particularly preferable to have a fixing cream composition inwhich at least the additives phosphoglyceride, silicon dioxide,trihydroxystearin and optionally polyethylene glycol are present incombination. Particularly suitable phosphoglycerides are lecithins.

A fixing cream composition in which at least the additives lecithin,silicon dioxide, polyethylene glycol and trihydroxystearin are presentin combination is very particularly preferable.

The plant oil and/or fat is preferably contained in the fixing cream ina quantity of at least 25% by weight, preferably at least 30% by weightin relation to the total quantity of the composition and the fatty acidcontent of the plant oil or fat preferably consists of at least 20% byweight, preferably at least 30% by weight, more preferably a majority,more preferably at least 65% by weight and more preferably at least 80%by weight, of higher fatty acids having a chain length of from 16 to 18C atoms.

The fatty acids of an added plant oil and/or fat, that is to say, theentirety of the fatty acids, generally consist of at least 20% byweight, preferably 40% by weight, more preferably 50% by weight,preferably 60% by weight, more preferably 70% by weight and mostpreferably at least 80% by weight of unsaturated fatty acids becausethis involves the advantage that the fixing cream is particularlytolerable for the prosthesis wearer during swallowing.

The higher fatty acids mentioned advantageously comprise a proportion offrom 50 to 90% by weight of oleic acid and a residual proportion ofother fatty acids having a chain length of from 16 to 18 C atoms. Morepreferably, the higher fatty acids comprise a proportion of from 50 to90% by weight of oleic acid, a proportion of from 5 to 25% by weight ofpalmitic acid and, optionally, a residual proportion of other fattyacids having a chain length of from 16 to 18 C atoms. The higher fattyacids more preferably comprise a proportion of from 50 to 90% by weightof oleic acid, a proportion of from 5 to 25% by weight of palmitic acid,a proportion of from 3 to 25% by weight of linoleic acid and,optionally, a residual proportion of other fatty acids having a chainlength of from 16 to 18 C atoms. Oils such as olive oil and rapeseed oilare included by the groups mentioned.

The plant oil and/or fat may expediently be provided in the unrefined orrefined state. The plant oil and/or fat is advantageously present in aquantity of from 25 to optionally 45% by weight in relation to the totalquantity of the composition. The quantity of plant oil or fat influencesthe consistency of the composition. If too little is added, the creammay take up a consistency which is dry in a granular manner. Theaddition of silicon dioxide, trihydroxystearin, phosphoglycerides andpolyethylene glycols can counteract this.

The cellulose derivatives are water-soluble polymers, preferablyselected from the group consisting of methyl cellulose, carboxymethylcellulose, sodium carboxymethyl cellulose, hydroxypropyl methylcellulose and admixtures thereof. Carboxymethyl cellulose, in particularsodium carboxymethyl cellulose, is preferably used. The water-solublepolymer selected from the group of cellulose derivatives is present in aquantity of from 15 to 45% by weight in relation to the total quantityof the composition. The water-soluble polymer selected from the group ofcellulose derivatives is preferably present in a quantity of from 20 to40% by weight and more preferably in a quantity of from 25 to 38% byweight in relation to the total quantity of the composition.

The alkyl vinyl ether/maleic acid anhydride copolymer is advantageouslypresent partially as an acid, ester and/or salt. Generally, the cationsof the salts are selected from the group consisting of calcium,potassium, sodium, magnesium, aluminium, zinc salts and admixturesthereof, in particular from the group consisting of Ca²⁺, K⁺, Na⁺, Mg²⁺,Al³⁺ and/or Zn²⁺. In particular, a methyl vinyl ether/maleic acidanhydride copolymer is used as the alkyl vinyl ether/maleic acidanhydride copolymer. The methyl vinyl ether/maleic acid anhydridecopolymer is present, for example, as a salt, ester and/or acid, in aquantity of from 20 to 45% by weight in relation to the total quantityof the composition. Advantageously, the methyl vinyl ether/maleic acidanhydride copolymer is present, for example, as a salt and/or acid in aquantity of from 25 to 45% by weight and preferably from 25 to 40% byweight and more preferably from 28 to 40% by weight in relation to thetotal quantity of the composition.

Zinc compounds are advantageously not present; that is to say, additionof zinc compounds is advantageously dispensed with. In particular inorder to minimise health risks owing to elevated absorption of zincowing to fixing creams, the zinc content should be limited to an upperlimit of a maximum of 1% by weight. That is to say that zinc may becontained in a quantity of up to 1% by weight in relation to the totalquantity of the composition. The zinc content should advantageously bebelow an upper limit of 1% by weight, preferably of 0.5% by weight, morepreferably of 0.1% by weight and more preferably of 0.06% by weight inrelation to the total quantity of the composition, respectively.

However, the absence of any zinc or any zinc compounds is mostpreferred. Zinc compounds having a lower limit of at least 0.001% byweight, preferably at least 0.01% by weight, more preferably at least0.02% by weight, more preferably at least 0.03% by weight in relation tothe total quantity of the composition are optionally present,respectively. In this instance, the upper limit and lower limit may befreely combined. In combination with the above-mentioned oil contents,the zinc quantity may be kept low. The lower limits result on the basisof a measurable effect (that is to say, influence of the adhesionproperties) or a desired effective strength as a result of the zinccontent.

Fixing creams having very good wearing properties and long-termstability values are particularly achieved when the above-mentioned oilor fat content, in particular of olive oil, is complied with.Alternatively or additionally, the preferred properties can be adjustedby using and optimising the stabilisers described.

Other additives such as, for example, flavourings, antioxidants andcolourings, are present in total in a quantity of a maximum of 10% byweight, preferably a maximum of 2% by weight and particularly preferablya maximum of 1% by weight in relation to the total quantity of thecomposition. With regard to the physiological harmlessness, the additionquantity of additives is kept as low as possible.

The invention is explained below with reference to examples. Theexamples set out compositions which ensure good adhesion strength andadhesion duration, in particular also under reduced pressure conditions.The percentages are rounded to two places after the decimal point.

Example 1

Component % by weight Olive oil ¹⁾ 40.35 Alkyl vinyl ether/maleic acidanhydride 30.26 copolymer Carboxymethyl cellulose 27.24 ZnO paste ²⁾0.10 Trihydroxystearin 2.02 Aromatic additive 0.03 ¹⁾ commerciallyavailable, ²⁾ the paste consists of 50% by weight of oil (for example,olive oil) and 50% by weight of zinc oxide (ZnO), consequentlyapproximately 0.04% by weight of zinc is added in the form of the ZnOpaste.

The fixing cream according to example 1 has good adhesion strength whichlasts at least 12 hours. The fixing cream leaves behind a fresh tasteand a good, pleasantly silky sensation in the mouth.

Example 2

Component % by weight Olive oil ¹⁾ 31.19 Alkyl vinyl ether/maleic acidanhydride 32.22 copolymer Carboxymethyl cellulose 36.38 ZnO paste ²⁾0.16 Trihydroxystearin 0.03 Lecithin 0.02 Aromatic additive ³⁾ 0.00 ¹⁾commercially available, ²⁾ the paste consists of 50% by weight of oil(for example, olive oil) and 50% by weight of zinc oxide (ZnO),consequently approximately 0.064% by weight of zinc is added in the formof the ZnO paste, ³⁾ the added quantity is below measurement accuracy,in particular below 0.01% by weight.

The fixing cream according to example 2 has good adhesion strength whichlasts at least 12 hours. The fixing cream leaves behind a fresh tasteand a good, pleasantly silky sensation in the mouth.

Example 3

Component % by weight Olive oil ¹⁾ 36.99 Alkyl vinyl ether/maleic acidanhydride 37.51 copolymer Carboxymethyl cellulose 24.91 ZnO paste ²⁾0.09 Trihydroxystearin 0.45 Lecithin 0.05 Aromatic additive ³⁾ 0.00 ¹⁾commercially available, ²⁾ the paste consists of 50% by weight of oil(for example, olive oil) and 50% by weight of zinc oxide (ZnO),consequently approximately 0.036% by weight of zinc is added in the formof the ZnO paste, ³⁾ the added quantity is below measurement accuracy,in particular below 0.01% by weight.

The fixing cream according to example 3 has good adhesion strength whichlasts at least 12 hours. The fixing cream leaves behind a fresh tasteand a good, pleasantly silky sensation in the mouth. This fixing creamfurther has good long-term stability over months and is consequentlystorable.

Example 4

Component % by weight Olive oil ¹⁾ 38.6 Alkyl vinyl ether/maleic acidanhydride 33 copolymer Carboxymethyl cellulose 20 Silicon dioxide 0.8Polyethylene glycol 7 Trihydroxystearin 0.4 Lecithin ²⁾ 0.2 Aromaticadditive ³⁾ — ¹⁾ commercially available, ²⁾ soya lecithin, ³⁾ optional.

The fixing cream according to example 4 has good adhesion strength whichlasts at least 12 hours. The fixing cream leaves behind a fresh tasteand a good, pleasantly silky sensation in the mouth. This fixing creamfurther also remains stable under reduced pressure conditions, as existin aircraft freight compartments and residential areas at highelevations.

Example 5

Component % by weight Olive oil ¹⁾ 38.58 Alkyl vinyl ether/maleic acidanhydride 33.00 copolymer Carboxymethyl cellulose 27.00Trihydroxystearin 0.40 Silicon dioxide ²⁾ 0.80 Lecithin ³⁾ 0.20 Aromas³⁾ 0.02 ¹⁾ commercially available, ²⁾ for example, pyrogenic silicondioxide, ³⁾ soya lecithin.

The fixing cream according to example 5 has good adhesion strength whichlasts at least 12 hours. The fixing cream leaves behind a fresh tasteand a good, pleasantly silky sensation in the mouth.

In summary, it is established that a plant oil and/or fat isadvantageously present in a quantity of from 25 to 60% by weight,preferably from 30 to 45% by weight in relation to the total quantity ofthe composition, the water-soluble polymer selected from the group ofcellulose derivatives is present in a quantity of from 10 to 40% byweight, preferably from 15 to 38% by weight, more preferably from 15 to25% by weight in relation to the total quantity of the composition, thealkyl vinyl ether/maleic acid anhydride copolymer is present in aquantity of from 25 to 45% by weight and preferably from 28 to 40% byweight in relation to the total quantity of the composition, the silicondioxide is present in a quantity of from 0 to 2.5% by weight andpreferably from 0 to 1.5% by weight in relation to the total quantity ofthe composition, the polyethylene glycol is present in a quantity offrom 0 to 15% by weight and preferably from 0 to 10% by weight inrelation to the total quantity of the composition, the trihydroxystearinis present in a quantity of from 0 to 2.5% by weight and preferably 2.1%by weight in relation to the total quantity of the composition and thephosphoglyceride is present in a quantity of from 0 to 3% by weight andpreferably from 0 to 2% by weight in relation to the total quantity ofthe composition. It was in particular established that thetrihydroxystearin is present in combination with the phosphoglyceride ina quantity of from 0 to 2.5% by weight and preferably from 0 to 1% byweight in relation to the total quantity of the composition. It wasfurther established that the total quantity of the trihydroxystearin,silicon dioxide and phosphoglyceride contained in total shouldpreferably not exceed the quantity of a maximum of 10% by weight,preferably a maximum of 5% by weight, more preferably a maximum of 4% byweight in relation to the total quantity of the composition.

1-20. (canceled)
 21. A composition of an adhesive cream, comprising: atleast one of a plant oil and a plant fat; at least one water-solublepolymer selected from the group consisting of cellulose derivatives; atleast one alkyl vinyl ether/maleic acid anhydride copolymer; andtrihydroxystearin.
 22. The composition of claim 21, further comprisingat least one other substance selected from the group consisting ofsilicon dioxide, phosphoglycerides and polyethylene glycols.
 23. Thecomposition of claim 22, wherein the silicon dioxide comprises 0.001 to5% by weight of the composition.
 24. The composition of claim 22,wherein the trihydroxystearin comprises 0.001 to 2.5% by weight of thecomposition.
 25. The composition of claim 23, wherein polyethyleneglycols comprise 0.001 to 15% by weight of the composition.
 26. Thecomposition of claim 25, wherein the polyethylene glycols have a molarmass in a range from 100,000 to 7,000,000 g/mol.
 27. The composition ofclaim 22, wherein the phosphoglycerides comprise 0.001 to 3% by weightof the composition.
 28. The composition of claim 22, wherein thephosphoglycerides are selected at least from the group consisting oflecithins.
 29. The composition of claim 21, further comprising talcum.30. The composition of claim 21, further comprising at least onelecithin.
 31. The composition of claim 30, further comprising at leastone other substance selected from the group consisting of silicondioxide and polyethylene glycol.
 32. The composition of claim 21,further comprising g silicon dioxide, polyethylene glycol and at leastone lecithin.
 33. The composition of claim 30, wherein the at least onelecithin comprises 0.001 to 3% by weight of the composition and thetrihydroxystearin comprises 0.001 to 2.5% by weight of the composition.34. The composition of claim 21, wherein the at least one of a plant oilor a plant fat comprises at least 25% by weight of the composition, anda fatty acid content of the at least one of a plant oil or a plant fatcomprised of a majority of higher fatty acids having a chain length offrom 16 to 18 C atoms.
 35. The composition of claim 34, wherein thefatty acid is comprised of at least 20% by weight of unsaturated fattyacids.
 36. The composition of claim 31, wherein a total content of thetrihydroxystearin, silicon dioxide and phosphoglycerides do not exceed amaximum of 10% by weight of the composition.
 37. The composition ofclaim 21, further comprising zinc in a quantity of less than 1% byweight of the composition.
 38. The composition of claim 37, wherein thezinc comprises between 0.01% by weight and 1% by weight of thecomposition.
 39. The composition of claim 21, further comprising from 25to 60% by weight of the at least one of a plant oil and a plant fat,from 10 to 40% by weight of the at least one water-soluble polymer, from25 to 45% by weight of the at least one alkyl vinyl ether/maleic acidanhydride copolymer, from 0 to 15% by weight of at least onepolyethylene glycol, from 0 to 3% by weight of at least onephosphoglyceride, from 0 to 2.5% by weight of trihydroxystearin, from 0to 5% by weight of silicon dioxide, and from 0 to 10% by weight of atleast one additive.
 40. The composition of claim 21, wherein the atleast one plant oil or plant fat comprises an olive oil.